Background & objectives: Iron deficiency anemia is a serious health issue affecting physical and psychological growth, behavior, and work performance. Teenage girls are among the groups who are at the risk of Iron deficiency anemia.‏ The aim of this research was to determine the effect of health education program based on PRECEDE Model in controlling iron-deficiency anemia.

Methods: This quasi-experimental study was done on 120 students (60 case and 60 control groups) who were selected using stratified random sampling method in 2013-2014.Intervention was done in three sessions of 60 minute and the questionnaires were distributed and completed three months later. Data gathering tool was a self-administered questionnaire base on the PRECEDE model constructs. Data were analyzed by independent and paired t-test, MaCNemar test using SPSS software version 18.

Results: Comparing to the control group, the mean scores of knowledge and attitude (predisposing factors), using educational resources, organizing educational course, participating in educational programs (Enabling factors), encouraging family , teachers and peers (reinforcing factors), and the practice significantly increased in the case group after educational intervention.

Conclusion: The present study indicates that an educational intervention based on PRECEDE model and its main components (predisposing, enabling, and reinforcing factors) has a positive effect on improving preventive behaviors of iron deficiency anemia in study population.