Background and Objectives: Along with industrial development, various pollutants release into the environment. The most toxic pollutants are Dioxins and Furans that enter to the environment from natural and anthropogenic sources. This study conducted to estimate Dioxin and Furan emission from various sources and determine source strength of pollutants in different provinces of Iran and their zoning in GIS. Methods: In order to achieve study targets, emission sources of Dioxin and Furan were identified and necessary data was then gathered using UNEP prepared questionnaire from relevant organizations. Emission rates were estimated applying UNEP suggested emission factors. Collected data then processed using Excel and Arc GIS softwares. Results: Total Dioxin and Furan emission was 1957 g for Iran in 2009. From this, 705.8, 0.5, 463.5, and 144.1 g were emitted to air, water, ground, and products, respectively and 643.2 g remain in residual ashes. Conclusion: This study shows that the emission rate of Dioxin and Furan is very high in Iran and that appropriate management strategies are required to control these dangerous pollutants.