Background & Objectives: In addition to supplying the needed water of human body, drinking water contains salts and minerals that are essential for the human body. Deficiency or excess of some of these minerals cause different problems and diseases. This study aimed to evaluate the effectiveness of home water treatment systems on reducing or eliminating the physical and chemical parameters in 2013. Methods: This was an analytical descriptive study. 12 water treatment units with different characteristics, in terms of the number of filters and filter life were selected from different locations that have different water sources including wells and surface water. Results: The results showed that mean removal efficiency of nitrate, nitrite, sulfate, chloride and fluoride by home water treatment systems, respectively are 79.16, 24.19, 48.5, 83.48, 72.86%.The average efficiency for removing of total hardness, calcium hardness, magnesium, Na, K, turbidity, and residual chlorine were respectively 82.41, 87.10, 65.78, 95.05, 79.48, 98.57, and 100%. Conclusion: Obtained results showed that home water treatment systems have very high efficiency to remove water physicochemical parameters. Using these systems are not necessary since most of the drinking water parameters are blow the Iran drinking water standards. In most cases they reduce the parameters to lower than the standard limits and decrease the taste and fluoride concentration to less than the standard values.