1. Bischoff SC, Boirie Y, Cederholm T, Chourdakis M, Cuerda C, Delzenne NM, et al. Towards a multidisciplinary approach to understand and manage obesity and related diseases. Clin Nutr. 2017;36(4):917-38. [DOI:10.1016/j.clnu.2016.11.007] [PMID]

2. Nguyen DM, El-Serag HB. The big burden of obesity. Gastrointest Endosc. 2009;70(4):752-7. [DOI:10.1016/j.gie.2009.04.003] [PMID]

3. Kobyliak N, Conte C, Cammarota G, Haley AP, Styriak I, Gaspar L, et al. Probiotics in prevention and treatment of obesity: a critical view. Nutr Metab (Lond). 2016;13(1):1-13. [DOI:10.1186/s12986-016-0067-0] [PMID] []

4. Fock KM, Khoo J. Diet and exercise in management of obesity and overweight. J Gastroenterol Hepatol. 2013;28:59-63. [DOI:10.1111/jgh.12407] [PMID]

5. Kalyani RR, Corriere M, Ferrucci L. Age-related and disease-related muscle loss: the effect of diabetes, obesity, and other diseases. lancet Diabetes Endocrinol. 2014;2(10):819-29. [DOI:10.1016/S2213-8587(14)70034-8] [PMID]

6. Geng C, Xia J, Wen D. Complications of obesity in children. Chinese J Appl Clin Pediatr. 2014;29(7):544-7.

7. Setoodeh A, Didban A, Rabbani A, Sayarifard A, Abbasi F, Sayarifard F, et al. The effect of metformin as an adjunct therapy in adolescents with type 1 diabetes. J Clin Diagnostic Res JCDR. 2017;11(4):SC01. [DOI:10.7860/JCDR/2017/24901.9725] [PMID] []

8. Kunin-Batson AS, Seburg EM, Crain AL, Jaka MM, Langer SL, Levy RL, et al. Household factors, family behavior patterns, and adherence to dietary and physical activity guidelines among children at risk for obesity. J Nutr Educ Behav. 2015;47(3):206-15. [DOI:10.1016/j.jneb.2015.01.002] [PMID] []

9. Schellekens H, Torres-Fuentes C, van de Wouw M, Long-Smith CM, Mitchell A, Strain C, et al. Bifidobacterium longum counters the effects of obesity: Partial successful translation from rodent to human. EBioMedicine. 2021;63:103176. [DOI:10.1016/j.ebiom.2020.103176] [PMID] []

10. Osterberg KL, Boutagy NE, McMillan RP, Stevens JR, Frisard MI, Kavanaugh JW, et al. Probiotic supplementation attenuates increases in body mass and fat mass during high-fat diet in healthy young adults. Obesity. 2015;23(12):2364-70. [DOI:10.1002/oby.21230] [PMID]

11. Boscaini S, Leigh S-J, Lavelle A, Garcia-Cabrerizo R, Lipuma T, Clarke G, et al. Microbiota and body weight control: Weight watchers within? Mol Metab. 2022;57:101427. [DOI:10.1016/j.molmet.2021.101427] [PMID] []

12. Everard A, Matamoros S, Geurts L, Delzenne NM, Cani PD. Saccharomyces boulardii administration changes gut microbiota and reduces hepatic steatosis, low-grade inflammation, and fat mass in obese and type 2 diabetic db/db mice. MBio. 2014;5(3):e01011--14. [DOI:10.1128/mBio.01011-14] [PMID] []

13. Kouhi F, Mirzaei H, Nami Y, Khandaghi J, Javadi A. Potential probiotic and safety characterisation of Enterococcus bacteria isolated from indigenous fermented Motal cheese. Int Dairy J. 2022;126:105247. [DOI:10.1016/j.idairyj.2021.105247]

14. Soleimani H, Shokri R, Nami Y, Khandaghi J, Panahi B. Potential probiotic characterization of lactic acid bacteria isolated from Duimaj, an Iranian traditional snack food, using biochemical, molecular and computational approaches. LWT. 2023;184:115091. [DOI:10.1016/j.lwt.2023.115091]

15. Wilkins T, Sequoia J. Probiotics for gastrointestinal conditions: a summary of the evidence. Am Fam Physician. 2017;96(3):170-8.

16. Derrien M, Turroni F, Ventura M, van Sinderen D. Insights into endogenous Bifidobacterium species in the human gut microbiota during adulthood. Trends Microbiol. 2022;30(10):940-947. [DOI:10.1016/j.tim.2022.04.004] [PMID]

17. Williams K, Oo T, Martirosyan D. Exploring the effectiveness of Lactobacillus probiotics in weight management: A literature review. Funct Food Sci. 2023;3(5):45-54. [DOI:10.31989/ffs.v3i5.1115]

18. Augagündüz D, Cocozza E, Cemali Ö, Bayazit AD, Nan'i MF, Cerqua I, et al. Understanding the role of the gut microbiome in gastrointestinal cancer: A review. Front Pharmacol. 2023;14:1130562. [DOI:10.3389/fphar.2023.1130562] [PMID] []

19. Pakbin B, Allahyari S, Dibazar SP, Zolghadr L, Chermahini NK, Brück WM, et al. Effects of Probiotic Saccharomyces boulardii Supernatant on Viability, Nano-Mechanical Properties of Cytoplasmic Membrane and Pro-Inflammatory Gene Expression in Human Gastric Cancer AGS Cells. Int J Mol Sci. 2023;24(9):7945. [DOI:10.3390/ijms24097945] [PMID] []

20. Mohammadi S, Aliakbarlu J, Tajik H, Manafi L, Mortazavi N. Inhibition of E. coli and bio-preservation of ground beef by Lactobacillus, black pepper extract and EDTA. Food Biosci. 2022;47:101635. [DOI:10.1016/j.fbio.2022.101635]

21. Pakbin B, Allahyari S, Dibazar SP, Peymani A, Haghverdi MK, Taherkhani K, et al. Anticancer Properties of Saccharomyces boulardii Metabolite Against Colon Cancer Cells. Probiotics Antimicrob Proteins. 2022;16(1):1-9. [DOI:10.1007/s12602-022-10030-w] [PMID]

22. Zajac AE, Adams AS, Turner JH. A systematic review and meta-analysis of probiotics for the treatment of allergic rhinitis. In: International forum of allergy & rhinology. 2015;5(6):524-32. [DOI:10.1002/alr.21492] [PMID] []

23. Salek F, Mirzaei H, Khandaghi J, Javadi A, Nami Y. Apoptosis induction in cancer cell lines and anti-inflammatory and anti-pathogenic properties of proteinaceous metabolites secreted from potential probiotic Enterococcus faecalis KUMS-T48. Sci Rep. 2023;13(1):7813. [DOI:10.1038/s41598-023-34894-2] [PMID] []

24. Knuesel T, Mohajeri MH. The role of the gut microbiota in the development and progression of major depressive and bipolar disorder. Nutrients. 2021;14(1):37. [DOI:10.3390/nu14010037] [PMID] []

25. Abenavoli L, Scarpellini E, Colica C, Boccuto L, Salehi B, Sharifi-Rad J, et al. Gut microbiota and obesity: a role for probiotics. Nutrients. 2019;11(11):2690. [DOI:10.3390/nu11112690] [PMID] []

26. Park D-Y, Ahn Y-T, Park S-H, Huh C-S, Yoo S-R, Yu R, et al. Supplementation of Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 in diet-induced obese mice is associated with gut microbial changes and reduction in obesity. PLoS One. 2013;8(3):e59470. [DOI:10.1371/journal.pone.0059470] [PMID] []

27. Yoo S-R, Kim Y-J, Park D-Y, Jung U-J, Jeon S-M, Ahn Y-T, et al. Probiotics L. plantarum and L. curvatus in combination alter hepatic lipid metabolism and suppress diet-induced obesity. Obesity. 2013;21(12):2571-8. [DOI:10.1002/oby.20428] [PMID]

28. Miao Z, Zheng H, Liu W-H, Cheng R, Lan H, Sun T, et al. Lacticaseibacillus paracasei k56 attenuates high-fat diet-induced obesity by modulating the gut microbiota in mice. Probiotics Antimicrob Proteins. 2022;15(4):1-12. [DOI:10.1007/s12602-022-09911-x] [PMID]

29. Sun Y, Chen S, Ren F, Li Y. Lactobacillus paracasei N1115 attenuates obesity in high-fat diet-induced obese mice. Food Sci Nutr. 2023;11(1):418-27. [DOI:10.1002/fsn3.3073] [PMID] []

30. Perna S, Ilyas Z, Giacosa A, Gasparri C, Peroni G, Faliva MA, et al. Is probiotic supplementation useful for the management of body weight and other anthropometric measures in adults affected by overweight and obesity with metabolic related diseases? A systematic review and meta-analysis. Nutrients. 2021;13(2):666. [DOI:10.3390/nu13020666] [PMID] []

31. Rahayu ES, Mariyatun M, Manurung NEP, Hasan PN, Therdtatha P, Mishima R, et al. Effect of probiotic Lactobacillus plantarum Dad-13 powder consumption on the gut microbiota and intestinal health of overweight adults. World J Gastroenterol. 2021;27(1):107. [DOI:10.3748/wjg.v27.i1.107] [PMID] []

32. Mo S-J, Lee K, Hong H-J, Hong D-K, Jung S-H, Park S-D, et al. Effects of Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 on overweight and the gut microbiota in humans: Randomized, double-blinded, placebo-controlled clinical trial. Nutrients. 2022;14(12):2484. [DOI:10.3390/nu14122484] [PMID] []

33. Sohn M, Jung H, Lee WS, Kim TH, Lim S. Effect of Lactobacillus plantarum LMT1-48 on body fat in overweight subjects: A randomized, double-blind, placebo-controlled trial. Korean Diabetes J. 2022;47(1):92-103. [DOI:10.4093/dmj.2021.0370] [PMID] []

34. Sohn M, Na GY, Chu J, Joung H, Kim B-K, Lim S. Efficacy and safety of Lactobacillus plantarum K50 on lipids in Koreans with obesity: A randomized, double-blind controlled clinical trial. Front Endocrinol (Lausanne). 2022;12:1906. [DOI:10.3389/fendo.2021.790046] [PMID] []

35. Kadeer G, Fu W, He Y, Feng Y, Liu W-H, Hung W-L, et al. Effect of different doses of Lacticaseibacillus paracasei K56 on body fat and metabolic parameters in adult individuals with obesity: a pilot study. Nutr Metab (Lond). 2023;20(1):1-15. [DOI:10.1186/s12986-023-00739-y] [PMID] []

36. Jung S-P, Lee K-M, Kang J-H, Yun S-I, Park H-O, Moon Y, et al. Effect of Lactobacillus gasseri BNR17 on overweight and obese adults: a randomized, double-blind clinical trial. Korean J Fam Med. 2013;34(2):80. [DOI:10.4082/kjfm.2013.34.2.80] [PMID] []

37. Kim J, Yun JM, Kim MK, Kwon O, Cho B. Lactobacillus gasseri BNR17 supplementation reduces the visceral fat accumulation and waist circumference in obese adults: a randomized, double-blind, placebo-controlled trial. J Med Food. 2018;21(5):454-61. [DOI:10.1089/jmf.2017.3937] [PMID]

38. Sanchez M, Darimont C, Drapeau V, Emady-Azar S, Lepage M, Rezzonico E, et al. Effect of Lactobacillus rhamnosus CGMCC1. 3724 supplementation on weight loss and maintenance in obese men and women. Br J Nutr. 2014;111(8):1507-19. [DOI:10.1017/S0007114513003875] [PMID]

39. Marcelo TLP, Pellicciari CR, Artioli TO, Leiderman DBD, Gradinar ALT, Mimica M, et al. Probiotic therapy outcomes in body composition of children and adolescent with obesity, a nonrandomized controlled trial. Arch Endocrinol Metab. 2022;66:815-22. [DOI:10.20945/2359-3997000000526] [PMID] []

40. Saros L, Vahlberg T, Koivuniemi E, Houttu N, Niinikoski H, Tertti K, et al. Fish oil and/or probiotics intervention in overweight/obese pregnant women and overweight risk in 24-month-old children. J Pediatr Gastroenterol Nutr. 2023;76(2):10-1097. [DOI:10.1097/MPG.0000000000003659] [PMID] []

41. Rajkumar H, Mahmood N, Kumar M, Varikuti SR, Challa HR, Myakala SP. Effect of probiotic (VSL# 3) and omega-3 on lipid profile, insulin sensitivity, inflammatory markers, and gut colonization in overweight adults: a randomized, controlled trial. Mediators Inflamm. 2014;2014: 348959. [DOI:10.1155/2014/348959] [PMID] []

42. Janczy A, Aleksandrowicz-Wrona E, Kochan Z, Małgorzewicz S. Impact of diet and synbiotics on selected gut bacteria and intestinal permeability in individuals with excess body weight--a prospective, randomized study. Acta Biochim Pol. 2020;67(4):571-8. [DOI:10.18388/abp.2020_5443] [PMID]

43. Kanazawa A, Aida M, Yoshida Y, Kaga H, Katahira T, Suzuki L, et al. Effects of synbiotic supplementation on chronic inflammation and the gut microbiota in obese patients with type 2 diabetes mellitus: a randomized controlled study. Nutrients. 2021;13(2):558. [DOI:10.3390/nu13020558] [PMID] []

44. Kassaian N, Feizi A, Rostami S, Aminorroaya A, Yaran M, Amini M. The effects of 6 mo of supplementation with probiotics and synbiotics on gut microbiota in the adults with prediabetes: A double blind randomized clinical trial. Nutrition. 2020;79:110854. [DOI:10.1016/j.nut.2020.110854] [PMID]

45. Peña F, Mizgier ML, Morales P, Rios I, Carrasco-Pozo C, Diaz E, et al. Effect of the synbiotic (B. animalis spp. lactis Bb12+ oligofructose) in obese subjects. A randomized, double-blind, controlled clinical trial. J Food Nutr Res. 2014;2(8):491-8. [DOI:10.12691/jfnr-2-8-10]

46. Krumbeck JA, Rasmussen HE, Hutkins RW, Clarke J, Shawron K, Keshavarzian A, et al. Probiotic Bifidobacterium strains and galactooligosaccharides improve intestinal barrier function in obese adults but show no synergism when used together as synbiotics. Microbiome. 2018;6:1-16. [DOI:10.1186/s40168-018-0494-4] [PMID] []

47. Hibberd AA, Yde CC, Ziegler ML, Honoré AH, Saarinen MT, Lahtinen S, et al. Probiotic or synbiotic alters the gut microbiota and metabolism in a randomised controlled trial of weight management in overweight adults. Benef Microbes. 2019;10(2):121-35. [DOI:10.3920/BM2018.0028] [PMID]

48. Yin Y-N, Yu Q-F, Fu N, Liu X-W, Lu F-G. Effects of four Bifidobacteria on obesity in high-fat diet induced rats. World J Gastroenterol WJG. 2010;16(27):3394. [DOI:10.3748/wjg.v16.i27.3394] [PMID] []

49. Chen J, Wang R, Li X-F, Wang R-L. Bifidobacterium adolescentis supplementation ameliorates visceral fat accumulation and insulin sensitivity in an experimental model of the metabolic syndrome. Br J Nutr. 2012;107(10):1429-34. [DOI:10.1017/S0007114511004491] [PMID]

50. Wang J, Tang H, Zhang C, Zhao Y, Derrien M, Rocher E, et al. Modulation of gut microbiota during probiotic-mediated attenuation of metabolic syndrome in high fat diet-fed mice. ISME J. 2015;9(1):1-15. [DOI:10.1038/ismej.2014.99] [PMID] []

51. Aller R, De Luis DA, Izaola O, Conde R, Gonzalez Sagrado M, Primo D, et al. Effect of a probiotic on liver aminotransferases in nonalcoholic fatty liver disease patients: a double blind randomized clinical trial. Eur Rev Med Pharmacol Sci. 2011;15(9):1090-5.

52. Thiennimitr P, Yasom S, Tunapong W, Chunchai T, Wanchai K, Pongchaidecha A, et al. Lactobacillus paracasei HII01, xylooligosaccharides, and synbiotics reduce gut disturbance in obese rats. Nutrition. 2018;54:40-7. [DOI:10.1016/j.nut.2018.03.005] [PMID]