Background & aim: Considering conducted studies on trust, health, and organizational entrepreneurship along with the lack of study on relationships among these three important organizational factors; present study aimed to survey correlations among organizational health and trust and entrepreneurship of employees.

Methods: This study was a correlational survey. The statistical population included 180 employees of Hamedan district and province health centers who were studied by questionnaire using census method. 122 of the completed questionnaires were reliable. Robbins and Coulter standard questionnaire with 22 questions was used to measure entrepreneurship variant and for the organizational trust and health a researcher-made questionnaire with 30 questions was administered. Reliability and validity were measured on the basis of Cronbach’s alpha and panel of experts. The collected data were analyzed by Pearson correlation coefficient, T test and regression analysis using SPSS software.

Results: The results of the study show that there are positive significant relationships between organizational trust and organizational health as well as the organizational health and entrepreneurship. However, no significant relationship was found between organizational trust and entrepreneurship.

Conclusion: Regarding the results of the study, some comments were given to managers to improve entrepreneurship through increasing organizational trust; with the hope to open new opportunities for further studies.